Dennie's lines are associated with which conjunctival condition?

Dennie's lines are associated with which conjunctival condition?

• A. VKC
• B. GPC
• C. Bacterial Conjunctivitis
• D. Atopic Keratoconjunctivitis

Answer: (D)

Dennie lines are a sign of chronic allergic inflammation seen in atopy. They appear as small, shallow folds below the lower lid (infra-tarsal area) from edema and tissue changes that develop with ongoing atopic disease. Because atopy often involves the eye in the form of atopic keratoconjunctivitis, these lashes-of-the-skin folds are most classically associated with that condition. In contrast, bacterial conjunctivitis is an infectious process with discharge rather than these chronic lid folds, and while vernal keratoconjunctivitis and giant papillary conjunctivitis are allergic, Dennie lines are most characteristically linked to atopic keratoconjunctivitis.

Dennie lines are a sign of chronic allergic inflammation seen in atopy. They appear as small, shallow folds below the lower lid (infra-tarsal area) from edema and tissue changes that develop with ongoing atopic disease. Because atopy often involves the eye in the form of atopic keratoconjunctivitis, these lashes-of-the-skin folds are most classically associated with that condition. In contrast, bacterial conjunctivitis is an infectious process with discharge rather than these chronic lid folds, and while vernal keratoconjunctivitis and giant papillary conjunctivitis are allergic, Dennie lines are most characteristically linked to atopic keratoconjunctivitis.