Which sign involves globe lag relative to lid movement when the patient looks upward?

Which sign involves globe lag relative to lid movement when the patient looks upward?

• A. Von Graefe's sign
• B. Kocher's sign
• C. Stellwag's sign
• D. Dalrymple's sign

Answer: (B)

In Graves orbitopathy, the extraocular muscles and surrounding tissues become inflamed and fibrotic, leading to abnormal coordination between eyelid and globe movements. Kocher's sign is the globe lag that occurs when the patient looks upward—the upper lid moves into position quickly, but the eyeball itself lags behind. This dyssynchrony reflects restricted or altered muscle function from the orbital inflammatory process.

In Graves orbitopathy, the extraocular muscles and surrounding tissues become inflamed and fibrotic, leading to abnormal coordination between eyelid and globe movements. Kocher's sign is the globe lag that occurs when the patient looks upward—the upper lid moves into position quickly, but the eyeball itself lags behind. This dyssynchrony reflects restricted or altered muscle function from the orbital inflammatory process.